Faraday Discussions: Volume 93 (1992)

Issue: Unassigned

• Contents pages (pp. P001-P004)
• Front cover (pp. X001-X002)
• Introductory lecture: what are enzyme structures telling us? (pp. 1-11) Perutz, M. F.
• Substrate recognition by proteinases (pp. 13-23) Hubbard, Simon J.; Thornton, Janet M.; Campbell, Simon F.
• Three-dimensional profiles for analysing protein sequence–structure relationships (pp. 25-34) Eisenberg, David; Bowie, James U.; Lüthy, Roland; Choe, Seunghyon
• Protein hydration in aqueous solution (pp. 35-45) Wüthrich, Kurt; Otting, Gottfried; Liepinsh, Edvards
• Functional zinc-binding motifs in enzymes and DNA-binding proteins (pp. 47-65) Vallee, Bert L.; Auld, David S.
• Structure and mechanism of D-xylose isomerase (pp. 67-73) Blow, David M.; Collyer, Charles A.; Goldberg, Jonathan D.; Smart, Oliver S.
• Three-dimensional structure of galactose oxidase: an enzyme with a built-in secondary cofactor (pp. 75-84) Ito, Nobutoshi; Phillips, Simon E. V.; Stevens, Conrad; Ogel, Zumrut B.; McPherson, Michael J.; Keen, Jeffery N.; Yadav, Kapil D. S.; Knowles, Peter F.
• Induced-fit movements in adenylate kinases (pp. 85-93) Schulz, Georg E.
• Structural and evolutionary relationships in lipase mechanism and activation (pp. 95-105) Dodson, G. Guy; Lawson, David M.; Winkler, Fritz K.
• General discussion (pp. 107-129) Eisenberg, D.; Perutz, M. F.; Buckingham, A. D.; Graf, L.; Thornton, J.; Blow, D. M.; Fersht, A. R.; Karplus, M.; Johnson, L. N.; Rippmann, F.; Dodson, G. G.; Edwards, P. N.; Halling, P.; Wüthrich, K.; Symons, M. C. R.; Marshall, K.; Vallee, B. L.; Rossi, M.; Auld, D. S.; Pombo-Villar, E.; Sinnott, M. L.; Dixon, H. B. F.; Berry, A.; Brown, D. R.; Littlechild, J. A.; Thomson, A.; Ito, N.; Knowles, P. F.; Taylor, S. S.; Schulz, G. E.; Misset, O.
• Catalytic mechanism of glycogen phosphorylase (pp. 131-142) Johnson, L. N.; Hu, S-H.; Barford, D.
• cAMP-dependent protein kinase and the protein kinase family (pp. 143-152) Taylor, Susan S.; Knighton, Daniel R.; Zheng, Jianhua; Eyck, Lynn F. Ten; Sowadski, Janusz M.
• Mechanism of allosteric transition of bacterial L-lactate dehydrogenase (pp. 153-162) Ohta, Takahisa; Yokota, Ken-ichi; Minowa, Takashi; Iwata, So
• Electron paramagnetic resonance studies of the mechanism of substrate oxidation by methane monooxygenase (pp. 163-171) Dalton, H.; Wilkins, P. C.; Deighton, N.; Podmore, I. D.; Symons, M. C. R.
• Dissection of protein structure and folding by directed mutagenesis (pp. 173-181) Baase, Walter A.; Eriksson, A. Elisabeth; Zhang, Xue-Jun; Heinz, Dirk W.; Sauer, Uwe; Blaber, Michael; Baldwin, Enoch P.; Wozniak, Joan A.; Matthews, Brian W.
• Pathway of protein folding (pp. 183-193) Fersht, Alan R.; Matouschek, Andreas; Sancho, Javier; Serrano, Luis; Vuilleumier, Stephane
• General discussion (pp. 195-215) Schulz, G. E.; Johnson, L. N.; Sinnott, M. L.; Perutz, M.; Taylor, S. S.; Karplus, M.; Ohta, T.; Edwards, P. N.; Blow, D. M.; Thornton, J.; Fersht, A. R.; Warshel, A.; Buckingham, A. D.; Eisenberg, D.; Dodson, G. G.; Williams, I. H.; Symons, M. C. R.; Matthews, B. W.; Wüthrich, K.; Graf, L.; Dalton, H.; Smart, O.; Rossi, M.; Lewis, R.
• Exploring the molecular mechanism of dihydrofolate reductase (pp. 217-224) Brown, Katherine A.; Kraut, Joseph
• Computer simulations of enzymatic reactions: examination of linear free-energy relationships and quantum-mechanical corrections in the initial proton-transfer step of carbonic anhydrase (pp. 225-238) Warshel, A.; Hwang, J. K.; Åqvist, J.
• Simulation analysis of triose phosphate isomerase: conformational transition and catalysis (pp. 239-248) Karplus, Martin; Evanseck, Jeffrey D.; Joseph, Diane; Bash, Paul A.; Field, Martin J.
• Cold destabilisation of enzymes (pp. 249-257) Hatley, Ross H. M.; Franks, Felix
• Vibrational Raman optical activity of enzymes (pp. 259-268) Barron, Laurence D.; Cooper, Alan; Ford, Steven J.; Hecht, Lutz; Wen, Zai Q.
• Modelling the structure and function of enzymes by machine learning (pp. 269-280) Sternberg, Michael J. E.; Lewis, Richard A.; King, Ross D.; Muggleton, Stephen
• General discussion (pp. 281-297) Charton, M.; Brown, K. A.; Schulz, G. E.; Warshel, A.; Kraut, J.; Pombo-Villar, E.; Fersht, A. R.; Karplus, M.; Williams, I. H.; Rubinson, K. A.; Eisenberg, D.; Buckingham, A. D.; Hillier, I. H.; Smart, O.; Deeth, R. J.; Owusu, R. K.; Hatley, R. H. M.; Franks, F.; Albrecht, A. C.; Barron, L. D.; Sinnott, M. L.; Fisher, L. R.; Brown, D. R.; Lewis, R.; King, R.; Perutz, M.; Leach, A. R.
• List of posters (pp. 299-300)
• List of participants (pp. 301-303)
• Index of contributors (pp. 305-305)
• General Discussions of the Faraday Society/Faraday Discussions of the Chemical Society (pp. 307-309)